Urinary Cytology – The Paris System (TPS) – Reporting – GUIDELINES – 2016

 

Publishing Authority: International Academy of Cytology

 

Includes:

1. Reporting categories

  • Nondiagnostic/unsatisfactory
  • Negative for high-grade urothelial carcinoma (NHGUC)
  • Atypical urothelial cells (AUC)
  • Suspicious for high-grade urothelial carcinoma (SHGUC)
  • High-grade urothelial carcinoma (HGUC)
  • Low-grade urothelial neoplasm (LGUN)
  • Other: primary and secondary malignancies and miscellaneous lesions

2. Criteria for atypical urothelial cells – One major and one minor criteria

  1. Major criterion (required): presence of nonsuperficial and nondegenerated urothelial cells with an increased nuclear:cytoplasmic (N:C) ratio of >0.5
  2. Minor criteria (any one of):
    1. mild nuclear hyperchromasia,
    2. irregular nuclear membranes (chromatinic rim or nuclear contour)
    3. irregular, coarse, clumped chromatin

 

Links:

Karger Full text: https://www.karger.com/Article/FullText/446270

Pubmed abstract: https://www.ncbi.nlm.nih.gov/pubmed/27233050

ScienceDirect abstract: https://www.sciencedirect.com/science/article/pii/S2213294516300448

Springer book purchase: https://www.springer.com/in/book/9783319228631

 

History:

  1. The Paris System Working Group was convened at the 2013 International Congress of Cytology, the guidelines were published by Springer International in 2016.
  2. Simultaneously published in the following journals: Advances in Anatomic Pathology, Acta Cytologica, and The Journal of the American Society of Cytopathology in 2016.

 

References:

  1. Rosenthal DL., Wojcik, EM., Kurtycz, DFI (Ed). The Paris System for Reporting Urinary Cytology. Springer International Publishing. 2016. Pathref accessibility score 0.
  2. Barkan GA, Wojcik EM, Nayar R, Savic-Prince S, Quek ML, Kurtycz DFI, Rosenthal DL. The Paris System for Reporting Urinary Cytology: The Quest to Develop a Standardized Terminology. Acta Cytologica 2016;60:185–197. (https://www.karger.com/Article/FullText/446270).Pathref accessibility score 4.
  3. Barkan GA, Wojcik EM, Nayar R, Savic-Prince S, Quek ML, Kurtycz DFI, Rosenthal DL. The Paris System for Reporting Urinary Cytology: The Quest to Develop a Standardized TerminologyAdvances in Anatomic Pathology. 23(4):193-201, July 2016. Pathref accessibility score 1.
  4. Barkan GA, Wojcik EM, Nayar R, Savic-Prince S, Quek ML, Kurtycz DFI, Rosenthal DL. The Paris System for Reporting Urinary Cytology: The Quest to Develop a Standardized Terminology. The Journal of the American Society of Cytopathology. Journal of the American Society of Cytopathology, 2016;5(3), 177-188. Pathref accessibility score 1.